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IMAPlateTM 5RC96 is developed based on our patent pending technology - Intelligent Multifunctional Analytic technology. It comprises 96 identical, funnel-like reaction units  to use capillary force to hold solution in its reaction units for reaction and / or for analysis in common 96-well plate readers. The standard 96-well plate format designing makes the IMAPlateTM 5RC96 suitable for both automated liquid handling systems and manual liquid handling.

                                            IMAPlateTM Technology      (click for larger image)

The unique concept of the technology makes liquid handling extremely simple and overcomes the obstacles arisen from handling tiny amount of solution in small sized well due to the miniaturization. Loading solution from the bottom opening by capillary action is self-dosed and in parallel, and emptying the loaded solution is just as simple as laying the IMAPlate on a filter paper. Up to 96 individual samples can simultaneously be loaded or emptied in seconds and it permits to manually perform efficient high-throughput application in every general laboratory. In addition, all options for pipette-based liquid handling, including automated liquid handling systems, are still retained when desired. The innovative  “go-through”  washing  procedure  simplifies  the  washing  step  and  increases  the  efficiency  of  removal  un-reacted  reagents  in  heterogeneous  reactions,  such  as  ELISA and solid phase chemical synthesis and so on.

                                                                                                             (click for larger image)

The special characteristics of the IMAPlateTM 5RC96 bring many advantages over conventional multi-well plate. The longer light-path length and bottomless of the capillarity reaction chambers can efficiently increase the detection sensitivity for absorbance readout in UV-Vis-IR full spectrum range. The larger surface area to volume ratio and the shorter diffusion distance can markedly speed up analyte binding to the surface in solid-phase reactions.

Besides, the intrinsic small volume requirements  of  the IMAPlateTM 5RC96  have  also  permitted applications  for  precious or limited sample sizes while also conserving  expensive  reagents.  For example, requirements for mouse serum sample size in IMAPlate-based ELISA have been reduced to no longer sacrifice animal, as it is the common cases for the conventional 96-well plate. Therefore, the  results  would be more reliable since the same mouse can be followed up on the way of animal studies. This also makes it possible to perform multianalyte measurements with ELISA from limited human serum or plasma in clinical trials.

Although it is a  simple  structured,  disposable  plastic  lab  device,  the  IMAPlateTM 5RC96  has integrated the features of many general lab devices and can serve as a versatile lab tool for research and routine work. For example, it can be used as a fixed volume 96-channel manual pipette for liquid handling, a 96-microcuvette  for  UV-Vis-IR  full  spectral  analysis, a  virtual 96-microwell plate for parallel reactions and assays, as well as a hanging drop cell culture device such as for stem cell, cell subcloning, multicellular tumor spheroids, and 3-D micro tissues preparation, testing and analysis. The easy-to-use,  flexible liquid handling and compatibility with 96-well plate reader make it an ideal tool for miniature  heterogeneous and  homogeneous assays to boost your productivity in lab. The IMAPlateTM 5RC96 represents the next generation of general lab devices and has very broad applications.